Heme and Iron

The mitochondrial enzyme, coproporphyrinogen III oxidase,
catalyzes the next reaction.

• The substrate is coproporphyrinogen III.
• The reaction is conversion of the propionic acid groups of rings I and III to vinyl groups. We now have the final substituent pattern of MV MV MP PM (note that "Petrarchan" pattern of the last four substituent groups).
• The product is protoporphyrinogen IX (pronounce). (Some naming systems would call this protoporphyrinogen III to preserve the logic of the nomenclature, but "protoporphyrinogen III" is a departure from a time-honored tradition of referring to this and subsequent compounds by the number "IX.")

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