![N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5](/web/image/product.product/60209/image_1024/%5BGEN-TR-D199032%5D%20N2'-Deacetyl-N2'-%5B3-%5B(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio%5D-1-oxopropyl%5D-maytansine-d5?unique=be6aa15)
N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5
Applications N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine-d5 is labelled N2'-Deacetyl-N2'-[3-[(1-ethyl-2,5-dioxo-3-pyrrolidinyl)thio]-1-oxopropyl]-maytansine (D199030), a derivative of Mertansine (M257800) which is a cytotoxic agent. It is used as the cytotoxic component in antibody-drug conjugates.
References Erickson, H., et al.: Cancer Res., 66, 4426 (2006); Kellogg, B., et al.: Bioconjugate Chem., 22, 717 (2011)