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Iron Porphyrins and Bioorganic Chemistry


Iron porphyrins are a central topic within the field of bioinorganic chemistry due to their key role in various biological systems, such as hemoglobin, myoglobin, and cytochrome enzymes. They serve as essential components for oxygen transport, electron transfer, and catalytic functions, making them an important area of study for understanding both natural and synthetic processes.

Key Publications and Works on Iron Porphyrins:

  1. Iron Porphyrins (Physical Bioinorganic Chemistry Series, Volumes 1-2, 4)
    • Authors/Editors: A. B. P. Lever and Harry B. Gray
    • These volumes are part of the Physical Bioinorganic Chemistry series and cover extensive research on iron porphyrins, exploring their chemical properties, structure-function relationships, and applications. They provide insights into how iron porphyrins participate in biological systems and can be engineered for synthetic applications.
  2. Iron Porphyrins Part III (Physical Bioinorganic Chemistry, Volume 4)
    • Editors: A. B. P. Lever, H. B. Gray, Phillip Lever
    • Published in June 1989, this hardcover volume is a continuation of the research on iron porphyrins, delving deeper into their bioinorganic chemistry. It includes discussions on the synthetic analogs of iron porphyrins, their electron-transfer properties, and their role in mimicking enzymatic processes.
  3. N-Substituted Porphyrins
    • Author: D. K. Lavallee
    • This book, available in both hardcover (August 1987) and paperback (November 1987), examines the chemistry and biochemistry of N-substituted porphyrins, offering a detailed analysis of how modifying the porphyrin structure impacts its chemical behavior and biological activity. N-substituted porphyrins are essential for the development of specialized catalysts and therapeutic agents.

Porphyrin Chemistry in Natural Products and Pesticides:

  1. Porphyric Pesticides: Chemistry, Toxicology, and Pharmaceutical Applications (ACS Symposium Series, 559)
    • Editors: Stephen O. Duke, Constantin A. Rebeiz
    • Published in May 1994, this volume discusses the applications of porphyrins in the design of pesticides, focusing on their unique chemical properties that allow for the development of environmentally friendly, biologically active compounds. It also explores the intersection of porphyrin chemistry with pharmaceutical applications.
  2. Comprehensive Natural Products Chemistry: Amino-Acids, Peptides, Porphyrins, and Alkaloids
    • Editors: Derek Barton, Koji Nakanishi, Otto Meth-Cohn
    • This comprehensive work addresses the chemistry of natural products, including the role of porphyrins alongside amino acids, peptides, and alkaloids. It provides a broader perspective on how porphyrins function within the context of natural and synthetic organic chemistry.

These publications offer a wealth of information for those interested in the complex world of porphyrins, their bioinorganic chemistry, and their practical applications in fields such as catalysis, medicine, and agriculture. By studying these texts, one can gain a deeper understanding of how porphyrins contribute to essential biological processes and how their unique properties can be harnessed for innovative solutions in science and industry.

https://www.researchgate.net/publication/229756286_Iron_Porphyrin_Chemistry